Amplify Creatine Absorption with These Key Nutrients

N-Acetyl Cysteine (NAC) and Glycine May Help Improve Key Markers of Aging

N-Acetyl Cysteine (NAC) and Glycine May Help Improve Key Markers of Aging

Glutathione (GSH) is the most abundant antioxidant in your body and plays an important role in health promotion.

The formation of glutathione (GSH) requires both cysteine (from NAC) and glycine, which may be why scientists are now finding GlyNAC supplementation provides a wide range of health benefits not provided by NAC-alone or Glutathione-alone. 

GlyNAC supplementation may be a novel nutritional approach to support healthy aging and improve key markers linked with aging, including: muscle strength, exercise capacity, cognition, and body composition.*

GlyNAC supplementation may be a novel nutritional approach to support healthy aging and improve key markers linked with aging, including*:

-Muscle strength and stem cells

-Exercise capacity

-Body composition

-Cognition and more

 

 

Related:

Support glutathione synthesis and detoxification of environmental pollutants* with NAC Glycine Supreme

Save 17% off the NAC + Glycine Supreme powder with code NAC17 at checkout through Sunday, October 15th at midnight PST

Here's a review of some resent studies:

Key Takeaways: 

01:00 N-acetylcysteine and glycine are rate limiting amino acids in glutathione production. 

01:00 Glutathione is comprised of glutamine, cystine, and glycine. 

02:40 Glycine-NAC supplementation improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, ageing hallmarks, metabolic defects, muscle strength, cognitive decline and body composition.

05:20 Taking direct antioxidants has conflicting evidence.

07:30 GGT liver enzyme is a marker of glutathione turnover.

References: 

Lizzo, G. et al. A Randomized Controlled Clinical Trial in Healthy Older Adults to Determine Efficacy of Glycine and N-Acetylcysteine Supplementation on Glutathione Redox Status and Oxidative Damage. Frontiers Aging 3, 852569 (2022).

 
Sekhar, R. V. GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes: Results of a Pilot Study. Antioxidants 11, 154 (2022).
 
Sekhar, R. V. GlyNAC Supplementation Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Aging Hallmarks, Metabolic Defects, Muscle Strength, Cognitive Decline, and Body Composition: Implications for Healthy Aging. J Nutrition 151, nxab309- (2021).
 
Sekhar, R. V. GlyNAC (Glycine and N-Acetylcysteine) Supplementation Improves Impaired Mitochondrial Fuel Oxidation and Lowers Insulin Resistance in Patients with Type 2 Diabetes: Results of a Pilot Study. Antioxidants 11, 154 (2022).
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.