Berberine HCl is a natural product that has been used in Chinese medicine for over 3,000 years. It's metabolic health benefits were discovered by accident when berberine was used to treat diarrhea in diabetic patients and practitioners observed it also supported healthy blood glucose metabolism*.

This video discusses a new study highlighing potential cardiovascular health* benefits of Berberine HCl. 

Related:

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Video Time Stamps:

00:00 Berberine has been used in Chinese medicine for 3,000 years.

00:23 Berberine may help support cardiovascular health.

00:52 In this study, Berberine was shown to regress plaque by 3.8% over 16 weeks.*

01:14 Historically Berberine HCl has been used to treat bacterial-induced diarrhea.

01:34 Berberine may be help Maintain Healthy Cholesterol Levels Already Within Normal Range*

02:14 Study dose of Berberine HCl was 500 mg, twice daily.

03:34 A reduction in TMAO was shown in a mouse study.

05:24 Berberine HCl acts on intestinal bacteria.

07:04 Berberine may upregulate LDL receptors on the liver.

Links to studies and videos mentioned:

Ma, S.-R. et al. Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota. Signal Transduct Target Ther 7, 207 (2022).

Cheng, H., Liu, J., Tan, Y., Feng, W. & Peng, C. Interactions between gut microbiota and berberine, a necessary procedure to understand the mechanisms of berberine. J Pharm Analysis 12, 541–555 (2022).

Patel, P. A bird’s eye view on a therapeutically ‘wonder molecule’: Berberine. Phytomedicine Plus (2021).