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Berberine Supports Metabolic Health, Belly Fat Loss in Women

Berberine has many health benefits, but one of the most compelling findings emerging from clinical trials is its connection to weight loss (specifically belly fat reduction).  

One recently published 12-week study compared the metabolic health related effects of Berberine, Metformin and Myo-Inositol. 

The investigators reported similar improvements in metabolic and hormonal health parameters with the three different interventions...

However, they observed greater belly fat loss and more favorable body composition changes in the group receiving berberine compared to the other interventions. 


Support metabolic health* and your Intermittent Fasting lifestyle with Berberine Fasting Accelerator
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Wei, W. et al. A clinical study on the short-term effect of berberine in comparison to metformin on the metabolic characteristics of women with polycystic ovary syndrome. Eur. J. Endocrinol. 166, 99–105 (2012).
Asbaghi, O., Ghanbari, N., Shekari, M., Reiner, Ž., Amirani, E., Hallajzadeh, J., Mirsafaei, L., & Asemi, Z. (2020). The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials. Clinical nutrition ESPEN38, 43–49.

Mishra N, Verma R, Jadaun P (January 31, 2022) Study on the Effect of Berberine, Myoinositol, and Metformin in Women with Polycystic Ovary Syndrome: A Prospective Randomised Study. Cureus 14(1): e21781. DOI 10.7759/cureus.21781

Time Stamps  

01:00 Berberine, myo-inositol, and Metformin induced significant changes in waist circumference, body composition, and metabolic parameters.

01:15 Berberine may help reduce cardiovascular disease risk in women*

03:30 Metformin, myoinositol and berberine can be used in combination.

05:45 Berberine group had a greater reduction in waist circumference.

07:11 Sex hormone binding globulin increased more in the berberine group.

07:20 Myo-inositol group improved fasting insulin better than berberine and Metformin.

09:14 Lipid related parameters improved in all groups, with berberine having the greater improvement

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

1 comment

  • Hello!
    I’m a very healthy, active (higher level amateur mountain runner), middle-aged women and after reading about all the amazing health benefits of berberine I decided to try it. I do not restrict carbs but I probably eat the bulk of them in the afternoon and at dinner and maybe as a snack after so I figured the best time to take it would be with dinner. I’ve tried taking 500 mg of berberine at dinner maybe 5 times now but it seems to affect my sleep negatively. Has anyone heard of this? Negative as in a higher resting heart rate the nights I take it and more disruptive. Anything I’ve found relating to sleep is that it should affect it positively. How would you handle this or maybe I shouldn’t be taking berberine in the first place? Thank you for the help.


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